Single-cell RNA-seq of lamina propria in wild type and LRRK2 G2019S mice after C. rodentium infectionWe performed 10X Genomics single-cell RNAsequencing of colonic lamina propria cells from wild type and LRRK2 G2019S mice following 1-week post C. rodentium infection. The cells were pooled from 3 mice per group of both sexes at 8-12 weeks of age. This dataset contains raw FASTQ files from mouse colonic lamina propria, sorted into 4 groups namely wild type and LRRK2 G2019S uninfected and infected mice. Sequencing was performed using NovaSeq 6000 S4 PE 100bp. Reads were processed using the 10X Genomics Cell Ranger Single Cell 2.0.0 pipeline. FASTQs generated from sequencing output were aligned to the mouse GRCm38 reference genome using STAR algorithm 2.7.3a. ASAP Team: Desjardins Dataset Name: desjardins-mouse-sc-rnaseq-colon-immune-lrrk2, v1.0 Principal Investigator: Michel Desjardins Co-Principal Investigator: Jo Stratton Contributors: Recinto, Sherilyn; Stratton, Jo Anne; Pei, Jessica; Gruenheid, Samantha Sample Summary: Resources and Additional Information Protocols GitHub: https://github.com/gruenheid-lab/pei-2024-lrrk2_neutrophil Protocols: https://doi.org/10.17504/protocols.io.bp2l6y5ervqe/v2 Dataset DOI: https://doi.org/10.5281/zenodo.20276410 Associated Publications:...Access requires approval by the data custodian. The collection's description and structure are public; querying the data requires an approved request.Single-cell RNA-seq of lamina propria in wild type and LRRK2 G2019S mice after C. rodentium infection is published on ASAP CRN Cloud.